You’re seeking a cocktail with bold character and depth. The Penicillin blends smoky Scotch, zesty ginger, honey, and fresh lemon to create a complex, soothing, and unforgettable drink. Its layered flavors—smoky, sweet, and tart—make it ideal for sipping slowly, impressing guests, or enjoying a refined nightcap that awakens the senses.
Equipment
To prepare The Penicillin, you’ll need:
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Cocktail shaker: For mixing ingredients evenly.
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Jigger or measuring cup: To measure exact quantities.
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Strainer: To pour smoothly into the glass.
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Rocks glass or Old Fashioned glass: Best for serving.
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Ice cubes: For chilling.
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Muddler (optional): For making fresh ginger syrup if desired.
Ingredients
Each ingredient contributes to The Penicillin’s bold and balanced profile:
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2 oz blended Scotch: Base spirit with smooth, malty flavor.
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0.75 oz fresh lemon juice: Provides bright, citrusy notes.
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0.75 oz honey-ginger syrup: Sweetness with subtle spice.
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0.5 oz Islay single malt (float): Adds a smoky finish.
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Ice cubes: For a chilled drink.
Optional garnish: candied ginger or lemon twist.
Instructions
Follow these steps to make a perfect Penicillin:
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Fill a cocktail shaker with ice cubes.
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Add blended Scotch, lemon juice, and honey-ginger syrup.
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Shake vigorously until well-chilled.
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Strain into a rocks glass filled with ice.
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Carefully float Islay single malt on top for a smoky layer.
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Garnish with a piece of candied ginger or a lemon twist.
Tasting Notes
The Penicillin is bold, balanced, and complex:
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Aroma: Smoky Scotch with honey and ginger undertones.
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Color: Golden amber, warm and inviting.
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Taste: Smooth and rich, sweet honey balanced by citrus and smoky finish.
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Mouthfeel: Medium-bodied, warming, and refreshing.
Similar Cocktails
Cocktails related in style or flavor include:
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Whiskey Sour: Lemon-forward with a sweet note, no smoke.
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Rob Roy: Scotch-based, but sweeter and stirred.
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Gold Rush: Bourbon, honey syrup, and lemon, without smoky notes.
History
The Penicillin was created in the early 2000s by bartender Sam Ross in New York City. Inspired by traditional remedies for colds and flu, the cocktail combines Scotch, honey, and ginger for a medicinal yet delicious flavor. Its modern classic status is cemented by its smoky, balanced taste and clever name.
Quick Pro Tips
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Use fresh lemon juice: Ensures bright citrus flavor.
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Float carefully: Pour the Islay Scotch slowly over the back of a spoon.
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Honey-ginger syrup: Can be made in advance for easy mixing.
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Adjust sweetness: Modify honey syrup to suit taste.
When to Serve
The Penicillin is perfect for:
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Evening cocktails or winter drinks: Warming and comforting.
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Sophisticated gatherings: Elegant, flavorful, and conversation-starting.
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Whiskey tasting sessions: Offers a smoky and balanced alternative.





